Please take the time to read this if you are not familiar with the story of Resident Evil, just so that RPG actually makes sense!

Resident Evil: The Story

Resident Evil is an extremely successful series of games based on the survival horror genre and is famed for the terror that it evoked in its fans.
The story revolves around a conspiracy involving the Pharmaceuticals company - Umbrella Inc which, whilst experimenting with it's prototype - 'T - Virus' created a virus that could mutate anything that it came into contact with. This experimentation was carried out in a remote mansion lab in the Arkly Mountains, a few miles from Raccoon City, where the RPG takes place.
Then, suddenly, the virus was accidentally released in the lab and all the inhabitants of the mansion were infected, resulting in their imminent death and return to 'life' as zombies. Also, Umbrella were working on a series of illegal experiments called B.O.W - or Bio Organic Weapons, basically Monsters, created by injecting the T-Virus into living tissue and animals, to create potential weapons. These monsters were set loose upon the release of the Virus.
Soon afterwards, a series of Murders in Raccoon City occurred, the evidence of which led the Arklay Labs. Raccoon's S.T.A.R.S (special tactics and rescue team) were sent to investigate, where they discovered the atrocities that Umbrella had committed, however, most of their team was wiped out and barely escaping with their lives, the Lab's self destruct system was activated and all evidence of the incident was destroyed. No one believed the S.T.A.R.S incredible accounts of the incident and everyone presumed them to be insane - until a few weeks later, another Prototype virus, the G-Virus, is released in the underground Labs in Raccoon city. The virus quickly spreads, infecting the entire city's population, leaving few survivors. This is where the RPG begins - with our survivors being caught in the middle of the nightmare with out a clue as to what is going on and only their wits and whatever weapons they can lay their hands on to help them escape the city alive...

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Here are the official plot summaries for the Resident Evil Games, 1,2 and 3. They are the ones which are most relevant to the RPG.

RESIDENT EVIL 1

For years a secluded mansion and its grounds have been the site of top-secret biotechnic experiments. The research staff has been funded by a respected (if slightly unethical) corporation named Umbrella. The weekly laboratory reports have been increasingly vague and now they have stopped completely. Recent gory attacks near the mansion have lead to rumors of unnatural canines on the prowl. Something has gone terribly wrong.
Two S.T.A.R.S. teams (Special Tactics and Rescue Squad) are sent to investigate these strange and gruesome developments. Bravo Team mobilizes first and disappears almost immediately. Alpha Team follows, urgently driven towards the mansion. As either Chris Redfield or Jill Valentine, two valuable parts of the Alpha team, you work your way inside. Everything is quiet... too quiet

RESIDENT EVIL 2

The story begins about a month and a half after the disaster at the mansion lab. Umbrella Corp develops the T-virus, a muta-genic toxin for the use in biological weapons. After breaking loose, living things mutate into all sorts of decaying creatures.
The case was eventually closed, but Umbrella's experience was far from over. Now it's the worst possible nightmare: a new virus runs rampant. All of Raccoon City is infested. Blood-thirsty zombies, hideous mutations now overwhelm the community. When Leon and Claire arrive in town their nightmare is just beginning. You must control their destiny. If the suspense doesn't kill you, something else will.

RESIDENT EVIL 3

A month and a half has passed since the incident. September has come to Raccoon City, a small industrial city in the American Midwest. People are starting to forget the chaos at the mansion as their lives return to normal.
The bizarre incident that occurred in the Arclay Mountains, the destruction of the special taskforce S.T.A.R.S., Umbrella's secret biological weapons laboratory hidden in an old mansion, the power of the T-Virus that turns humans and animals into horrible monsters... how could it all happen here?

People could not believe the survivors' reports. Stories of their incredible experiences and of strange biological weapons and zombies were beyond the townsfolks' imagination. The surviving S.T.A.R.S. team members headed to Europe even before the town heard the full details of what had happened.

They hoped it was all over. But then it happened again. Suddenly a series of inexplicable murders occurred and a strange disease began invading neighborhoods. T-Virus was flowing into the city...

The invisible plague snuck up silently and turned the unsuspecting citizens into monsters. People cursed their foolishness, but the nightmare had already begun. The future was out of their control.

Raccoon City was on the brink of collapse...